A gene, a mutation in which increases the risk of ovarian cancer by almost 10 times, was discovered by American researchers.

Scientists reported that we are talking about the RAD15D gene. On average, mutations in this gene occur in one in 70 women. Ovarian cancer leads to the death of 60% of patients and takes about 4200 lives a year. On average, only 4 patients out of 10 survive with ovarian cancer. Therefore, doctors do not exclude that women themselves will decide whether to leave their ovaries or remove them after the birth of children in order to prevent the development of cancer. Professor Nazneen Rahman, head of genetics and epidemiology at the Institute for Cancer Research, said : “At this level of risk, women may wish to consider having their ovaries removed after having children to prevent cancer.” He claims that scientists are developing drugs designed specifically for this gene.
The study was based on DNA comparisons between 911 women with a family history of ovarian and breast cancer and 1,060 women without a diagnosis. One in 10 cases of ovarian cancer occurs in women who have relatives with ovarian and breast cancer in the family, the scientists explained. Experts believe that the results of this study will help to individualize the approach to treating patients and give doctors more information about the risks of the disease.

Now experts intend to continue research in the field of genetic engineering in order to learn how to “repair” damaged genes. The researchers do not rule out that drugs known as PPA inhibitors, which work against cancers caused by mutations in the BRCA1 https://en.wikipedia.org/wiki/BRCA1 gene, may also help with mutations in RAD51D.